Iran launched a new wave of missile attacks on Israel early Monday, triggering air raid sirens across the country as emergency services reported at least three killed and dozens more wounded in the fourth day of open warfare between the regional foes.

Iran announced it had launched some 100 missiles and vowed further retaliation for the surprise attack on its nuclear programme and military leadership that Israel began last Friday.

Powerful explosions, likely from Israel's defence systems intercepting Iranian missiles, rocked Tel Aviv shortly before dawn on Monday, sending plumes of black smoke into the sky over the coastal city.